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Salinomycin kills cancer stem cells in different types of human cancers by interfering with ABC drug transporters, the View chapterPurchase book. 13 Nov 2019 Uveal melanoma (UM) is the most common primary intraocular tumor. Hepatic metastasis is the major and direct death-related reason in UM Treatment of 5 mg/kg salinomycin in mice implanted with SUM159 human breast cancer cells inhibits mammary tumor growth and induces increased epithelial 14 Feb 2019 Objectives Salinomycin is a polyether antibiotic with selective activity against human cancer stem cells. The impact of salinomycin on Salinomycin toxicity in turkeys has been reported on numerous occasions.
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Bioz Stars score: 90/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more 2017-03-28 · There are very few drugs available in market which target CSCs. Salinomycin is known for selective killing CSCs and sensitizing tumor cells at a very low concentration. It has exhibited toxicity over a broad range of cancers.
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